George A. Carlson

Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

Alix de Calignon, Manuela Polydoro, Marc Suárez‐Calvet et al. · Neuron · 2012 · 1.4K citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Tau Pathology +11

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice

Martin Citron, David Westaway, Weiming Xia et al. · Nature Medicine · 1997 · 1.3K citations

Neurodegenerative Diseases, Alzheimer's Disease, Molecular Neuroscience +12

Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration

Brian R. Hoover, Miranda N. Reed, Jianjun Su et al. · Neuron · 2010 · 1.1K citations · Full text

Synaptic Plasticity, Neurodegenerative Diseases, Cortical Remodeling +10

Early-onset Amyloid Deposition and Cognitive Deficits in Transgenic Mice Expressing a Double Mutant Form of Amyloid Precursor Protein 695

M. Azhar Chishti, Dun-Shen Yang, Christopher Janus et al. · Journal of Biological Chemistry · 2001 · 947 citations · Full text

Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication

Stanley B. Prusiner, Michael Scott, Dallas Foster et al. · Cell · 1990 · 867 citations

Biology, Transgenetic Studies, Natural Sciences +9