Donald E. Awrey

Functional Characterization of CFI-400945, a Polo-like Kinase 4 Inhibitor, as a Potential Anticancer Agent

Jacqueline M. Mason, Dan Lin, Wei Xin et al. · Cancer Cell · 2014 · 195 citations · Full text

Chemoprevention Strategy, Medicine, Receptor Tyrosine Kinase +12

The Discovery of Polo-Like Kinase 4 Inhibitors: Identification of (1<i>R</i>,2<i>S</i>)-2-(3-((<i>E</i>)-4-(((<i>cis</i>)-2,6-Dimethylmorpholino)methyl)styryl)-1<i>H</i>-indazol-6-yl)-5′-methoxyspiro[cyclopropane-1,3′-indolin]-2′-one (CFI-400945) as a Potent, Orally Active Antitumor Agent

Peter B. Sampson, Yong Liu, Bryan Forrest et al. · Journal of Medicinal Chemistry · 2014 · 166 citations · Full text

Screening for Ligands Using a Generic and High-Throughput Light-Scattering-Based Assay

Guillermo Senisterra, Eugene Markin, Ken Yamazaki et al. · SLAS DISCOVERY · 2006 · 129 citations · Full text

Transcription Elongation through DNA Arrest Sites

Donald E. Awrey, Rodney G. Weilbaecher, Sally A. Hemming et al. · Journal of Biological Chemistry · 1997 · 109 citations · Full text

Mode of Action, <i>In Vitro</i> Activity, and <i>In Vivo</i> Efficacy of AFN-1252, a Selective Antistaphylococcal FabI Inhibitor

Nachum Kaplan, Monique Albert, Donald E. Awrey et al. · Antimicrobial Agents and Chemotherapy · 2012 · 109 citations · Full text