Joseph M. Gruber

2-Amino-3-substituted-6-[(<i>E</i>)-1-phenyl-2-(<i>N</i>-methylcarbamoyl)vinyl]imidazo[1,2-<i>a</i>]pyridines as a Novel Class of Inhibitors of Human Rhinovirus:  Stereospecific Synthesis and Antiviral Activity

Chafiq Hamdouchi, Jesús de Blas, Mirian del Prado et al. · Journal of Medicinal Chemistry · 1998 · 279 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Pharmacological characterization of LY335979: A potent cyclopropyldibenzosuberane modulator of P-glycoprotein

James J. Starling, Robert L. Shepard, Jin Cao et al. · Advances in Enzyme Regulation · 1997 · 86 citations

Medicine, Medicinal Chemistry, Pharmacology +5

Tricyclic isoxazoles are novel inhibitors of the multidrug resistance protein (MRP1)

Bryan H. Norman, Joseph M. Gruber, Sean P. Hollinshead et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 66 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

Cyclohexyl-linked tricyclic isoxazoles are potent and selective modulators of the multidrug resistance protein (MRP1)

Bryan H. Norman, Peter A. Lander, Joseph M. Gruber et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 54 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

Synthesis and biological evaluation of novel cryptophycin analogs with modification in the β-alanine region

Chuan Shih, Lynn S. Gossett, Joseph M. Gruber et al. · Bioorganic & Medicinal Chemistry Letters · 1999 · 49 citations

Pharmacy, Medicinal Chemistry, Pharmacology +8