Concepedia

Cyclohexyl-linked tricyclic isoxazoles are potent and selective modulators of the multidrug resistance protein (MRP1)

Bryan H. Norman, Peter A. Lander, Joseph M. Gruber, Julian S. Kroin, Jeffrey Cohen, Louis N. Jungheim, James J. Starling, Kevin L. Law, Tracy D. Self, Linda B. Tabas,

Bioorganic & Medicinal Chemistry Letters · 2005 · 54 citations · 6 references

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6

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

Susan P.C. Cole, Gabu Bhardwaj, James H. Gerlach et al. · Science · 1992 · 3.1K citations

, , +16

Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells.

Susan P.C. Cole, Kathryn E. Sparks, Karen Fraser et al. · PubMed · 1994 · 774 citations

, , +15

ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein.

Gabriele Jedlitschky, Inka Leier, Ulrike Buchholz et al. · PubMed · 1994 · 437 citations

, , +10

Tricyclic isoxazoles are novel inhibitors of the multidrug resistance protein (MRP1)

Bryan H. Norman, Joseph M. Gruber, Sean P. Hollinshead et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 66 citations · Full text

, , +9

Inhibitors of MRP1-mediated multidrug resistance

Bryan H. Norman · Drugs of the Future · 1998 · 29 citations

, , +9