Julian S. Kroin

Evaluation of the antitumor activity of gemcitabine (2',2'-difluoro-2'-deoxycytidine).

Larry W. Hertel, G B Boder, Julian S. Kroin et al. · PubMed · 1990 · 683 citations

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Chemistry +14

Pharmacological characterization of LY335979: A potent cyclopropyldibenzosuberane modulator of P-glycoprotein

James J. Starling, Robert L. Shepard, Jin Cao et al. · Advances in Enzyme Regulation · 1997 · 86 citations

Molecular Pharmacology, Pharmacological Characterization, Biochemistry +6

Cyclohexyl-linked tricyclic isoxazoles are potent and selective modulators of the multidrug resistance protein (MRP1)

Bryan H. Norman, Peter A. Lander, Joseph M. Gruber et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 54 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Drug Target +13

Liquid chromatography/nuclear magnetic resonance spectroscopy and liquid chromatography/mass spectrometry identification of novel metabolites of the multidrug resistance modulator LY335979 in rat bile and human liver microsomal incubations.

William J. Ehlhardt, Joseph M. Woodland, Todd M. Baughman et al. · PubMed · 1998 · 40 citations

Metabolomic Profiling, Medicinal Chemistry, Novel Metabolites +20

Effect of a template-located 2',2'-difluorodeoxycytidine on the kinetics and fidelity of base insertion by Klenow (3'-->5'exonuclease-) fragment.

William E. Schy, Larry W. Hertel, Julian S. Kroin et al. · PubMed · 1993 · 34 citations

Bioorganic Chemistry, Dna Analysis, Molecular Biology +17