Janet C. Lynn

Tipranavir (PNU-140690):  A Potent, Orally Bioavailable Nonpeptidic HIV Protease Inhibitor of the 5,6-Dihydro-4-hydroxy-2-pyrone Sulfonamide Class

Steve R. Turner, Joseph W. Strohbach, Rubén Tommasi et al. · Journal of Medicinal Chemistry · 1998 · 296 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structure-Based Design of HIV Protease Inhibitors:  Sulfonamide-Containing 5,6-Dihydro-4-hydroxy-2-pyrones as Non-Peptidic Inhibitors

Suvit Thaisrivongs, Harvey I. Skulnick, Steve R. Turner et al. · Journal of Medicinal Chemistry · 1996 · 96 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Structure-Based Design of Novel HIV Protease Inhibitors:  Sulfonamide-Containing 4-Hydroxycoumarins and 4-Hydroxy-2-pyrones as Potent Non-Peptidic Inhibitors

Suvit Thaisrivongs, Musiri N. Janakiraman, Kong-Teck Chong et al. · Journal of Medicinal Chemistry · 1996 · 88 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Structure-Based Design of HIV Protease Inhibitors:  5,6-Dihydro-4-hydroxy-2-pyrones as Effective, Nonpeptidic Inhibitors

Suvit Thaisrivongs, Donna L. Romero, Rubén Tommasi et al. · Journal of Medicinal Chemistry · 1996 · 86 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structure-Based Design of Nonpeptidic HIV Protease Inhibitors:  The Sulfonamide-Substituted Cyclooctylpyranones

Harvey I. Skulnick, Paul D. Johnson, Paul A. Aristoff et al. · Journal of Medicinal Chemistry · 1997 · 85 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacokinetics +12