Warren W. Ku

The application of structure-based assessment to support safety and chemistry diligence to manage genotoxic impurities in active pharmaceutical ingredients during drug development

Krista L. Dobo, Nigel Greene, Michelle O. Cyr et al. · Regulatory Toxicology and Pharmacology · 2006 · 127 citations

Structure-based Assessment, Medicinal Chemistry, Drug Purity +16

Strategy for genotoxicity testing—Metabolic considerations

Warren W. Ku, Anita Bigger, Giovanni Brambilla et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2006 · 111 citations

Medicine, Toxicology Testing, Genotoxicity Testing—metabolic Considerations +4

Tissue disposition of boron in male Fischer rats

Warren W. Ku, Robert E. Chapin, Robert F. Moseman et al. · Toxicology and Applied Pharmacology · 1991 · 108 citations

Animal Physiology, Tissue Disposition, Animal Science +7

Spermatocyte Toxicity of 2-Methoxyethanol (ME) in Rats and Guinea Pigs: Evidence for the Induction of Apoptosis

Warren W. Ku, Robert N. Wine, Younbyoung Chae et al. · Toxicology and Applied Pharmacology · 1995 · 69 citations

Infertility, Andrology, Fertility +12

Genotoxicity profiles of common alkyl halides and esters with alkylating activity

Zhanna Sobol, Maria Engel, Elizabeth Rubitski et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2007 · 69 citations

Derivative (Chemistry), Engineering, Medicine +10