Frank P. Buxton

Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening

E. Robert McDonald, Antoine de Weck, Michael R. Schlabach et al. · Cell · 2017 · 701 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +17

Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers

Gregory R. Hoffman, Rami Rahal, Frank P. Buxton et al. · Proceedings of the National Academy of Sciences · 2014 · 416 citations · Full text

Life Sciences, Genetics, Oncology +17

Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells

Vadim Iourgenko, Wenjun Zhang, Craig Mickanin et al. · Proceedings of the National Academy of Sciences · 2003 · 371 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Role of the cysteine protease cathepsin S in neuropathic hyperalgesia

J. Elaine Barclay, Anna K. Clark, Pam Ganju et al. · Pain · 2007 · 133 citations

Life Sciences, Neurobiology, Neuroscience +17

The polygalacturonases of <i>Aspergillus niger</i> are encoded by a family of diverged genes

H. J. D. Bussink, Frank P. Buxton, Bartholomeus A. FRAAYE et al. · European Journal of Biochemistry · 1992 · 124 citations

Life Sciences, Genetics, Molecular Biology +17