Sarah Grimwood

Design and Selection Parameters to Accelerate the Discovery of Novel Central Nervous System Positron Emission Tomography (PET) Ligands and Their Application in the Development of a Novel Phosphodiesterase 2A PET Ligand

Lei Zhang, Anabella Villalobos, Elizabeth M. Beck et al. · Journal of Medicinal Chemistry · 2013 · 199 citations · Full text

Pet Ligands, Pet-mri, Novel Phosphodiesterase 2A +16

4-Amido-2-carboxytetrahydroquinolines. Structure-activity relationships for antagonism at the glycine site of the NMDA receptor

Paul D. Leeson, Robert W. Carling, Kevin W. Moore et al. · Journal of Medicinal Chemistry · 1992 · 187 citations · Full text

Effect of Plasma Protein Binding on in Vivo Activity and Brain Penetration of Glycine/NMDA Receptor Antagonists

Michael Rowley, Janusz J. Kulagowski, Alan P. Watt et al. · Journal of Medicinal Chemistry · 1997 · 129 citations

Brain Penetration, Glycine/nmda Receptor Antagonists, Pharmacotherapy +18

Identification of Molecular Determinants That Are Important in the Assembly of N-Methyl-d-aspartate Receptors

Elisabeth Meddows, B. Le Bourdellès, Sarah Grimwood et al. · Journal of Biological Chemistry · 2001 · 114 citations · Full text

Duration of Action of a Broad Range of Selective κ-Opioid Receptor Antagonists Is Positively Correlated with c-Jun N-Terminal Kinase-1 Activation

Erica J. Melief, Mayumi Miyatake, F. Ivy Carroll et al. · Molecular Pharmacology · 2011 · 104 citations · Full text