Tian Wu

Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin

Sheng Chu Kuo, Hong Zin Lee, Jung Pin Juang et al. · Journal of Medicinal Chemistry · 1993 · 195 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

Network pharmacology-based study on the mechanism of action for herbal medicines in Alzheimer treatment

Jiansong Fang, Ling Wang, Tian Wu et al. · Journal of Ethnopharmacology · 2016 · 123 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +16

Discovery and Optimization of a Series of Benzothiazole Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors

Noel D. D’Angelo, Tae‐Seong Kim, Kristin L. Andrews et al. · Journal of Medicinal Chemistry · 2011 · 119 citations · Full text

Pharmacy, Oncology, Pharmacology +14

Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers

Marc Payton, Brian Belmontes, Kelly Hanestad et al. · Nature Cancer · 2023 · 68 citations · Full text

Life Sciences, Cell Biology, Oncology +17

Reactive oxygen species-mitochondria pathway involved in LYG-202-induced apoptosis in human hepatocellular carcinoma HepG2 cells

Feihong Chen, Linbo Zhang, Lei Qiang et al. · Cancer Letters · 2010 · 50 citations

Life Sciences, Cell Biology, Oncology +16