Yuzuru Kanakura

Gain-of-Function Mutations of c- <i>kit</i> in Human Gastrointestinal Stromal Tumors

Seiichi Hirota, Koji Isozaki, Y Moriyama et al. · Science · 1998 · 4.5K citations

Medicine, Genetics, Oncology +17

A new protein containing an SH2 domain that inhibits JAK kinases

Takaho A. Endo, Masaaki Masuhara, Masahiro Yokouchi et al. · Nature · 1997 · 1.4K citations

Life Sciences, Cell Biology, Molecular Biology +16

Humanized anti–interleukin-6 receptor antibody treatment of multicentric Castleman disease

Norihiro Nishimoto, Yuzuru Kanakura, Katsuyuki Aozasa et al. · Blood · 2005 · 750 citations · Full text

Pharmacy, Immunology, Pharmacotherapy +12

Anti-CCR4 mAb selectively depletes effector-type FoxP3 ⁺ CD4 ⁺ regulatory T cells, evoking antitumor immune responses in humans

Daisuke Sugiyama, Hiroyoshi Nishikawa, Yuka Maeda et al. · Proceedings of the National Academy of Sciences · 2013 · 620 citations · Full text

Life Sciences, Immunology, Oncology +17

Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways

Masao Mizuki, R. Fenski, Hartmut Halfter et al. · Blood · 2000 · 581 citations

Medicine, Genetics, Molecular Biology +9