Eslam E. Abd El-Fattah

The dynamic interplay between AMPK/NFκB signaling and NLRP3 is a new therapeutic target in inflammation: Emerging role of dapagliflozin in overcoming lipopolysaccharide-mediated lung injury

Eslam E. Abd El-Fattah, Sameh Saber, Ahmed A.E. Mourad et al. · Biomedicine & Pharmacotherapy · 2022 · 85 citations · Full text

Life Sciences, Immunology, Pharmacology +17

A Novel Combination Therapy Using Rosuvastatin and Lactobacillus Combats Dextran Sodium Sulfate-Induced Colitis in High-Fat Diet-Fed Rats by Targeting the TXNIP/NLRP3 Interaction and Influencing Gut Microbiome Composition

Sameh Saber, Eslam E. Abd El-Fattah, Galal Yahya et al. · Pharmaceuticals · 2021 · 70 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Interference With the AMPKα/mTOR/NLRP3 Signaling and the IL-23/IL-17 Axis Effectively Protects Against the Dextran Sulfate Sodium Intoxication in Rats: A New Paradigm in Empagliflozin and Metformin Reprofiling for the Management of Ulcerative Colitis

Mahmoud E. Youssef, Eslam E. Abd El-Fattah, Hanan Eissa et al. · Frontiers in Pharmacology · 2021 · 60 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Empagliflozin adjunct with metformin for the inhibition of hepatocellular carcinoma progression: Emerging approach for new application

Sameh Saber, Mahmoud E. Youssef, Ahmed Gaafar Ahmed Gaafar et al. · Biomedicine & Pharmacotherapy · 2021 · 60 citations · Full text

Medicine, Oncology, Pharmacology +12

Blunting p38 MAPKα and ERK1/2 activities by empagliflozin enhances the antifibrotic effect of metformin and augments its AMPK-induced NF-κB inactivation in mice intoxicated with carbon tetrachloride

Mahmoud E. Youssef, Eslam E. Abd El-Fattah, Naglaa A. Gobba et al. · Life Sciences · 2021 · 40 citations · Full text

Life Sciences, Cell Biology, Pharmacology +13