Mahmoud E. Youssef

BBG enhances OLT1177-induced NLRP3 inflammasome inactivation by targeting P2X7R/NLRP3 and MyD88/NF-κB signaling in DSS-induced colitis in rats

Sameh Saber, Mahmoud E. Youssef, Hossam Sharaf et al. · Life Sciences · 2021 · 68 citations

Inflammation, Chronic Inflammatory Diseases, Mucosal Immunology +14

Empagliflozin adjunct with metformin for the inhibition of hepatocellular carcinoma progression: Emerging approach for new application

A. M. Abdelhamid, Sameh Saber, Mahmoud E. Youssef et al. · Biomedicine & Pharmacotherapy · 2021 · 58 citations · Full text

Interference With the AMPKα/mTOR/NLRP3 Signaling and the IL-23/IL-17 Axis Effectively Protects Against the Dextran Sulfate Sodium Intoxication in Rats: A New Paradigm in Empagliflozin and Metformin Reprofiling for the Management of Ulcerative Colitis

Mahmoud E. Youssef, Eslam E. Abd El-Fattah, A. M. Abdelhamid et al. · Frontiers in Pharmacology · 2021 · 54 citations · Full text

Canagliflozin-loaded chitosan-hyaluronic acid microspheres modulate AMPK/NF-κB/NLRP3 axis: A new paradigm in the rectal therapy of ulcerative colitis

Mohamed Nasr, Simona Cavalu, Sameh Saber et al. · Biomedicine & Pharmacotherapy · 2022 · 45 citations · Full text

Ambroxol, a mucolytic agent, boosts <scp>HO</scp> ‐1, suppresses <scp>NF‐κB</scp> , and decreases the susceptibility of the inflamed rat colon to apoptosis: A new treatment option for treating ulcerative colitis

Simona Cavalu, Hossam Sharaf, Sameh Saber et al. · The FASEB Journal · 2022 · 44 citations