Hossam Sharaf

BBG enhances OLT1177-induced NLRP3 inflammasome inactivation by targeting P2X7R/NLRP3 and MyD88/NF-κB signaling in DSS-induced colitis in rats

Sameh Saber, Mahmoud E. Youssef, Hossam Sharaf et al. · Life Sciences · 2021 · 68 citations

Inflammation, Chronic Inflammatory Diseases, Mucosal Immunology +14

Vildagliptin, a DPP-4 inhibitor, attenuates carbon tetrachloride-induced liver fibrosis by targeting ERK1/2, p38α, and NF-κB signaling

Rania M. Khalil, Ahmed Shata, Eman M. Abd El-Kader et al. · Toxicology and Applied Pharmacology · 2020 · 61 citations

Immunology, Pathology, Tetrachloride-induced Liver Fibrosis +16

Celastrol augments sensitivity of NLRP3 to CP-456773 by modulating HSP-90 and inducing autophagy in dextran sodium sulphate-induced colitis in rats

Sameh Saber, Eman M. Abd El-Kader, Hossam Sharaf et al. · Toxicology and Applied Pharmacology · 2020 · 48 citations

Inflammation, Anti-inflammatory, Autoimmune Disease +8

Ambroxol, a mucolytic agent, boosts <scp>HO</scp> ‐1, suppresses <scp>NF‐κB</scp> , and decreases the susceptibility of the inflamed rat colon to apoptosis: A new treatment option for treating ulcerative colitis

Simona Cavalu, Hossam Sharaf, Sameh Saber et al. · The FASEB Journal · 2022 · 44 citations

The Supportive Role of NSC328382, a P2X7R Antagonist, in Enhancing the Inhibitory Effect of CRID3 on NLRP3 Inflammasome Activation in Rats with Dextran Sodium Sulfate-Induced Colitis

Sameh Saber, Galal Yahya, Naglaa A. Gobba et al. · Journal of Inflammation Research · 2021 · 37 citations · Full text