Naglaa A. Gobba

BBG enhances OLT1177-induced NLRP3 inflammasome inactivation by targeting P2X7R/NLRP3 and MyD88/NF-κB signaling in DSS-induced colitis in rats

Sameh Saber, Mahmoud E. Youssef, Hossam Sharaf et al. · Life Sciences · 2021 · 74 citations

Life Sciences, Immunology, Pathobiology +14

A Novel Combination Therapy Using Rosuvastatin and Lactobacillus Combats Dextran Sodium Sulfate-Induced Colitis in High-Fat Diet-Fed Rats by Targeting the TXNIP/NLRP3 Interaction and Influencing Gut Microbiome Composition

Sameh Saber, Eslam E. Abd El-Fattah, Galal Yahya et al. · Pharmaceuticals · 2021 · 70 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Interference With the AMPKα/mTOR/NLRP3 Signaling and the IL-23/IL-17 Axis Effectively Protects Against the Dextran Sulfate Sodium Intoxication in Rats: A New Paradigm in Empagliflozin and Metformin Reprofiling for the Management of Ulcerative Colitis

Mahmoud E. Youssef, Eslam E. Abd El-Fattah, Hanan Eissa et al. · Frontiers in Pharmacology · 2021 · 60 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Albendazole-loaded cubosomes interrupt the ERK1/2-HIF-1α-p300/CREB axis in mice intoxicated with diethylnitrosamine: A new paradigm in drug repurposing for the inhibition of hepatocellular carcinoma progression

Sameh Saber, Mohamed Nasr, Ahmed S. Saad et al. · Biomedicine & Pharmacotherapy · 2021 · 45 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +16

Blunting p38 MAPKα and ERK1/2 activities by empagliflozin enhances the antifibrotic effect of metformin and augments its AMPK-induced NF-κB inactivation in mice intoxicated with carbon tetrachloride

Mahmoud E. Youssef, Eslam E. Abd El-Fattah, Naglaa A. Gobba et al. · Life Sciences · 2021 · 40 citations · Full text

Life Sciences, Cell Biology, Pharmacology +13