Ahmed Gaafar Ahmed Gaafar

Empagliflozin adjunct with metformin for the inhibition of hepatocellular carcinoma progression: Emerging approach for new application

A. M. Abdelhamid, Sameh Saber, Mahmoud E. Youssef et al. · Biomedicine & Pharmacotherapy · 2021 · 58 citations · Full text

Interference With the AMPKα/mTOR/NLRP3 Signaling and the IL-23/IL-17 Axis Effectively Protects Against the Dextran Sulfate Sodium Intoxication in Rats: A New Paradigm in Empagliflozin and Metformin Reprofiling for the Management of Ulcerative Colitis

Mahmoud E. Youssef, Eslam E. Abd El-Fattah, A. M. Abdelhamid et al. · Frontiers in Pharmacology · 2021 · 54 citations · Full text

Canagliflozin-loaded chitosan-hyaluronic acid microspheres modulate AMPK/NF-κB/NLRP3 axis: A new paradigm in the rectal therapy of ulcerative colitis

Mohamed Nasr, Simona Cavalu, Sameh Saber et al. · Biomedicine & Pharmacotherapy · 2022 · 45 citations · Full text

Coomassie brilliant blue G-250 dye attenuates bleomycin-induced lung fibrosis by regulating the NF-κB and NLRP3 crosstalk: A novel approach for filling an unmet medical need

Mona H. Zohny, Simona Cavalu, Mahmoud E. Youssef et al. · Biomedicine & Pharmacotherapy · 2022 · 40 citations · Full text

Inflammatory Lung Disease, Lung Inflammation, Immunology +18

Blunting p38 MAPKα and ERK1/2 activities by empagliflozin enhances the antifibrotic effect of metformin and augments its AMPK-induced NF-κB inactivation in mice intoxicated with carbon tetrachloride

A. M. Abdelhamid, Mahmoud E. Youssef, Eslam E. Abd El-Fattah et al. · Life Sciences · 2021 · 38 citations · Full text