Toshiyuki Otsuka

Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor

Hisashi Takayama, William J. LaRochelle, Richard Sharp et al. · Proceedings of the National Academy of Sciences · 1997 · 439 citations · Full text

C-Met Autocrine Activation Induces Development Of Malignant Melanoma And Acquisition Of The Metastatic Phenotype

Toshiyuki Otsuka, Hisashi Takayama, Richard Sharp et al. · PubMed · 1998 · 269 citations · Full text

Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis

Richard Sharp, Juan A. Recio, Chamelli Jhappan et al. · Nature Medicine · 2002 · 157 citations

Signal Transduction, Signaling Pathway, Medicine +6

Hepatocyte growth factor promotes hepatocarcinogenesis through c-Met autocrine activation and enhanced angiogenesis in transgenic mice treated with diethylnitrosamine

Norio Horiguchi, Hisashi Takayama, Mitsuo Toyoda et al. · Oncogene · 2002 · 116 citations

Hepatocyte Growth Factor, Hepatology, Liver Physiology +9

Accelerated ultraviolet radiation-induced carcinogenesis in hepatocyte growth factor/scatter factor transgenic mice.

Frances P. Noonan, Toshiyuki Otsuka, S Bang et al. · PubMed · 2000 · 105 citations

Radiation Effect, Pathology, Cell Proliferation +16