Joseph A. Martin

Rational Design of Peptide-Based HIV Proteinase Inhibitors

Noel A. Roberts, Joseph A. Martin, Derek Kinchington et al. · Science · 1990 · 925 citations

Life Sciences, Biochemistry, Medicinal Chemistry +17

The Novel Nucleoside Analog R1479 (4′-Azidocytidine) Is a Potent Inhibitor of NS5B-dependent RNA Synthesis and Hepatitis C Virus Replication in Cell Culture

Klaus Klumpp, Vincent Lévêque, Sophie Le Pogam et al. · Journal of Biological Chemistry · 2005 · 215 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +15

Use of a Pharmacophore Model To Discover a New Class of Influenza Endonuclease Inhibitors

K. E. B. PARKES, Philipp Ermert, Jürg Fässler et al. · Journal of Medicinal Chemistry · 2003 · 142 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Studies toward the Large-Scale Synthesis of the HIV Proteinase Inhibitor Ro 31-8959

K. E. B. PARKES, D. J. BUSHNELL, Peter H. Crackett et al. · The Journal of Organic Chemistry · 1994 · 98 citations

Life Sciences, Medicinal Chemistry, Pharmacology +7

Design, synthesis, and antiviral properties of 4′-substituted ribonucleosides as inhibitors of hepatitis C virus replication: The discovery of R1479

David B. Smith, Joseph A. Martin, Klaus Klumpp et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 97 citations

Pharmacy, Biochemistry, Medicinal Chemistry +16