Thia St Martin

Discovery of a Mutant-Selective Covalent Inhibitor of EGFR that Overcomes T790M-Mediated Resistance in NSCLC

Annette O. Walter, Robert Tjin Tham Sjin, Henry J. Haringsma et al. · Cancer Discovery · 2013 · 622 citations · Full text

Selective irreversible inhibition of a protease by targeting a noncatalytic cysteine

Margit Hagel, Deqiang Niu, Thia St Martin et al. · Nature Chemical Biology · 2010 · 92 citations

Selective Irreversible Inhibition, Biochemistry, Protein Folding +8

Discovery of a Potent and Isoform-Selective Targeted Covalent Inhibitor of the Lipid Kinase PI3Kα

Mariana Nacht, Lixin Qiao, Michael P. Sheets et al. · Journal of Medicinal Chemistry · 2013 · 85 citations · Full text

Drug Target, Chemical Biology, Cancer Biology +18

<i>In Vitro</i> and <i>In Vivo</i> Characterization of Irreversible Mutant-Selective EGFR Inhibitors That Are Wild-Type Sparing

Robert Tjin Tham Sjin, Kwangho Lee, Annette O. Walter et al. · Molecular Cancer Therapeutics · 2014 · 70 citations

Drug Targeting, Novel Therapy, Normal Lung Tissue +14

Protein tyrosine phosphatase PRL-3 in malignant cells and endothelial cells: expression and function

Cécile Rouleau, André Roy, Thia St Martin et al. · Molecular Cancer Therapeutics · 2006 · 64 citations · Full text