Guido van Mierlo

Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma

Gerard L. Brien, David Remillard, Junwei Shi et al. · eLife · 2018 · 212 citations · Full text

Synovial Sarcoma, Oncogenic Agent, Medicine +15

PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation

Evan Healy, Marlena Mucha, Eleanor Glancy et al. · Molecular Cell · 2019 · 205 citations · Full text

Natural Sciences, Proton Transfer, Molecular Biology +3

MTF2 recruits Polycomb Repressive Complex 2 by helical-shape-selective DNA binding

Matteo Perino, Guido van Mierlo, Ino D. Karemaker et al. · Nature Genetics · 2018 · 180 citations

Chromatin, Chromatin Structure, Protein Assembly +10

Dynamics of gene silencing during X inactivation using allele-specific RNA-seq

Hendrik Marks, Hindrik H. D. Kerstens, Tahsin Stefan Barakat et al. · Genome biology · 2015 · 139 citations · Full text

In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states

Alex Neagu, Emiel van Genderen, Irene Escudero‐Martínez et al. · Nature Cell Biology · 2020 · 133 citations · Full text

Embryo Culture, Embryonic Rosette-stage Pluripotency, Embryonic Stem Cell +12