Gerard L. Brien

Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands

David Remillard, Dennis L. Buckley, Joshiawa Paulk et al. · Angewandte Chemie International Edition · 2017 · 278 citations · Full text

Chemical Biology, Inorganic Chemistry, Heterobifunctional Ligands +15

Polycomb PHF19 binds H3K36me3 and recruits PRC2 and demethylase NO66 to embryonic stem cell genes during differentiation

Gerard L. Brien, Guillermo Gambero, David O’Connell et al. · Nature Structural & Molecular Biology · 2012 · 253 citations

Stem Cell Genes, Genetics, Stem Cell Biology +16

Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma

Gerard L. Brien, David Remillard, Junwei Shi et al. · eLife · 2018 · 212 citations · Full text

Synovial Sarcoma, Oncogenic Agent, Medicine +15

NUP98 Fusion Proteins Interact with the NSL and MLL1 Complexes to Drive Leukemogenesis

Haiming Xu, Daria G. Valerio, Meghan E. Eisold et al. · Cancer Cell · 2016 · 162 citations · Full text

Mll1 Complexes, Medicine, Tumor Suppressor +5

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells

Giorgio Oliviero, Gerard L. Brien, Ariane Waston et al. · Molecular & Cellular Proteomics · 2016 · 79 citations · Full text