Simon Dawson

Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas

Hiroaki Higashitsuji, Katsuhiko Itoh, Toshikazu Nagao et al. · Nature Medicine · 2000 · 298 citations

Tumor Biology, Oncogenic Ankyrin-repeat Protein, Retinoblastoma Protein +7

The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53

Hiroaki Higashitsuji, Hisako Higashitsuji, Katsuhiko Itoh et al. · Cancer Cell · 2005 · 227 citations · Full text

Tumor Biology, Oncoprotein Gankyrin, Medicine +6

Gankyrin Is an Ankyrin-repeat Oncoprotein That Interacts with CDK4 Kinase and the S6 ATPase of the 26 S Proteasome

Simon Dawson, Sébastien Apcher, Maureen Mee et al. · Journal of Biological Chemistry · 2002 · 120 citations · Full text

MAGE-A4 Interacts with the Liver Oncoprotein Gankyrin and Suppresses Its Tumorigenic Activity

Toshikazu Nagao, Hiroaki Higashitsuji, Kohsuke Nonoguchi et al. · Journal of Biological Chemistry · 2003 · 106 citations · Full text

The Crystal Structure of Gankyrin, an Oncoprotein Found in Complexes with Cyclin-dependent Kinase 4, a 19 S Proteasomal ATPase Regulator, and the Tumor Suppressors Rb and p53

Szymon Krzywda, A.M. Brzozowski, Hiroaki Higashitsuji et al. · Journal of Biological Chemistry · 2004 · 87 citations · Full text