Auke D. Adema

Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models

Andries M. Bergman, Auke D. Adema, Jan Balzarini et al. · Investigational New Drugs · 2010 · 95 citations · Full text

Medicine, Oncology, Pharmacology +15

Metabolism and accumulation of the lipophilic deoxynucleoside analogs elacytarabine and CP-4126

Auke D. Adema, Kees Smid, Nienke Losekoot et al. · Investigational New Drugs · 2011 · 51 citations · Full text

Medicine, Oncology, Pharmacology +17

Overexpression of MRP4 (ABCC4) and MRP5 (ABCC5) confer resistance to the nucleoside analogs cytarabine and troxacitabine, but not gemcitabine

Auke D. Adema, Karijn Floor, Kees Smid et al. · SpringerPlus · 2014 · 31 citations · Full text

Medicine, Oncology, Pharmacology +13

Trifluorothymidine Resistance Is Associated with Decreased Thymidine Kinase and Equilibrative Nucleoside Transporter Expression or Increased Secretory Phospholipase A2

Olaf H. Temmink, Irene V. Bijnsdorp, Henk‐Jan Prins et al. · Molecular Cancer Therapeutics · 2010 · 30 citations · Full text

Medicine, Oncology, Pharmacology +17

Sulfasalazine Down-Regulates the Expression of the Angiogenic Factors Platelet-Derived Endothelial Cell Growth Factor/Thymidine Phosphorylase and Interleukin-8 in Human Monocytic-Macrophage THP1 and U937 Cells

Michiel de Bruin, Godefridus J. Peters, Ruud Oerlemans et al. · Molecular Pharmacology · 2004 · 17 citations

Life Sciences, Immunology, Pharmacology +17