Sourav Saha

PARylation prevents the proteasomal degradation of topoisomerase I DNA-protein crosslinks and induces their deubiquitylation

Yilun Sun, Jiji Chen, Shar-yin N. Huang et al. · Nature Communications · 2021 · 72 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Resolution of R-loops by topoisomerase III-β (TOP3B) in coordination with the DEAD-box helicase DDX5

Sourav Saha, Xi Yang, Shar-yin N. Huang et al. · Cell Reports · 2022 · 70 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

A Novel Spirooxindole Derivative Inhibits the Growth of Leishmania donovani Parasites both <i>In Vitro</i> and <i>In Vivo</i> by Targeting Type IB Topoisomerase

Sourav Saha, Chiranjit Acharya, Uttam Pal et al. · Antimicrobial Agents and Chemotherapy · 2016 · 61 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Synthesis, computational studies and antiproliferative activities of coumarin-tagged 1,3,4-oxadiazole conjugates against MDA-MB-231 and MCF-7 human breast cancer cells

Sanjeev Dhawan, Nagaraju Kerru, Paul Awolade et al. · Bioorganic & Medicinal Chemistry · 2018 · 61 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks

Sourav Saha, Yilun Sun, Shar-yin N. Huang et al. · Cell Reports · 2020 · 56 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15