Shin Iimura

Discovery of 3-(3-(4-(1-Aminocyclobutyl)phenyl)-5-phenyl-3<i>H</i>-imidazo[4,5-<i>b</i>]pyridin-2-yl)pyridin-2-amine (ARQ 092): An Orally Bioavailable, Selective, and Potent Allosteric AKT Inhibitor

Jean‐Marc Lapierre, Sudharshan Eathiraj, David Vensel et al. · Journal of Medicinal Chemistry · 2016 · 105 citations · Full text

Pharmaceutical Science, Pharmacotherapy, Pharmaceutical Chemistry +18

Enantioselective Total Synthesis of Guanacastepene N Using an Uncommon 7-Endo Heck Cyclization as a Pivotal Step

Shin Iimura, Larry E. Overman, Ralph Paulini et al. · Journal of the American Chemical Society · 2006 · 92 citations

7-Endo Heck Cyclization, Novel Organocatalysts, Enantioselective Synthesis +14

Synthesis and Structure-Activity Relationships of Novel 2',2'-Difluoro Analogues of Docetaxel.

Kouichi Uoto, Satoru Ohsuki, H. TAKENOSHITA et al. · Chemical and Pharmaceutical Bulletin · 1997 · 80 citations · Full text

Pharmaceutical Science, Several 2',2'-Difluoro Derivatives, Organic Chemistry +18

New highly active taxoids from 9β-Dihydrobaccatin-9,10-acetals

Takashi Ishiyama, Shin Iimura, Satoru Ohsuki et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 26 citations

Biosynthesis, Bioorganic Chemistry, Biochemistry +4

Discovery of Novel Pyrido-pyridazinone Derivatives as FER Tyrosine Kinase Inhibitors with Antitumor Activity

Toru Taniguchi, Hiroaki Inagaki, Daichi Baba et al. · ACS Medicinal Chemistry Letters · 2019 · 26 citations · Full text