Jean‐Marc Lapierre

Identification of the Binding Site for a Novel Class of CCR2b Chemokine Receptor Antagonists

Tara Mirzadegan, Frank Diehl, Bettina Ebi et al. · Journal of Biological Chemistry · 2000 · 249 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Discovery of 3-(3-(4-(1-Aminocyclobutyl)phenyl)-5-phenyl-3<i>H</i>-imidazo[4,5-<i>b</i>]pyridin-2-yl)pyridin-2-amine (ARQ 092): An Orally Bioavailable, Selective, and Potent Allosteric AKT Inhibitor

Jean‐Marc Lapierre, Sudharshan Eathiraj, David Vensel et al. · Journal of Medicinal Chemistry · 2016 · 111 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery and Optimization of a Series of 3-(3-Phenyl-3<i>H</i>-imidazo[4,5-<i>b</i>]pyridin-2-yl)pyridin-2-amines: Orally Bioavailable, Selective, and Potent ATP-Independent Akt Inhibitors

Mark A. Ashwell, Jean‐Marc Lapierre, Christopher J. Brassard et al. · Journal of Medicinal Chemistry · 2012 · 100 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Chiral Dendrimers from Tris(hydroxymethyl)methane Derivatives

Dieter Seebàch, Jean‐Marc Lapierre, Konstantinos Skobridis et al. · Angewandte Chemie International Edition in English · 1994 · 87 citations

Natural Sciences, Chemistry, Materials Science +7

Preclinical Activity of ARQ 087, a Novel Inhibitor Targeting FGFR Dysregulation

Terence Hall, Yi Yu, Sudharshan Eathiraj et al. · PLoS ONE · 2016 · 85 citations · Full text

Medicine, Oncology, Pharmacology +17