Concepedia

Sudharshan Eathiraj

SE

Statistics

Publications

20

Citations

2K

H-Index

19

Active since

2003

Affiliations

Arqule (United States)(Current)

University of Massachusetts Chan Medical School

The Ohio State University

Sarah Cannon

South Texas Accelerated Research Therapeutics

Sudharshan Eathiraj is an author at Arqule (United States) specializing in oncology, pharmacology, and medicine.

ORCID

Publications per year

2003–2023

20

Publications

20

TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism

Xiaojing Pan, Sudharshan Eathiraj, Mary Munson et al. · Nature · 2006 · 349 citations

, , +7

Structural basis of family-wide Rab GTPase recognition by rabenosyn-5

Sudharshan Eathiraj, Xiaojing Pan, C. Ritacco et al. · Nature · 2005 · 240 citations · Full text

, , +14

The BTK Inhibitor ARQ 531 Targets Ibrutinib-Resistant CLL and Richter Transformation

Sean D. Reiff, Rose Mantel, Lisa L. Smith et al. · Cancer Discovery · 2018 · 170 citations · Full text

, , +17

Discovery of a Novel Mode of Protein Kinase Inhibition Characterized by the Mechanism of Inhibition of Human Mesenchymal-epithelial Transition Factor (c-Met) Protein Autophosphorylation by ARQ 197

Sudharshan Eathiraj, Rocio Palma, Erika Volckova et al. · Journal of Biological Chemistry · 2011 · 139 citations · Full text

, , +16

Targeting AKT1-E17K and the PI3K/AKT Pathway with an Allosteric AKT Inhibitor, ARQ 092

Yi Yu, Ronald E. Savage, Sudharshan Eathiraj et al. · PLoS ONE · 2015 · 121 citations · Full text

, , +14

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