David T. Parker

Discovery of CGS 27023A, a Non-Peptidic, Potent, and Orally Active Stromelysin Inhibitor That Blocks Cartilage Degradation in Rabbits

Lawrence MacPherson, Erol K. Bayburt, Michael Capparelli et al. · Journal of Medicinal Chemistry · 1997 · 325 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Quinolizidine synthesis via intramolecular immonium ion based Diels-Alder reactions. Total synthesis of (.+-.)-lupinine, (.+-.)-epilupinine, (.+-.)-cryptopleurine, and (.+-.)-julandine

Paul A. Grieco, David T. Parker · The Journal of Organic Chemistry · 1988 · 59 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8

Retro aza Diels-Alder reactions: acid catalyzed heterocycloreversion of 2-azanorbornenes in water at ambient temperature

Paul A. Grieco, David T. Parker, Michael J. Cornwell et al. · Journal of the American Chemical Society · 1987 · 59 citations

Natural Sciences, Chemistry, Analytical Chemistry +7

Discovery of Potent, Selective, and Orally Active Carboxylic Acid Based Inhibitors of Matrix Metalloproteinase-13

Lauren G. Monovich, Rubén Tommasi, Roger A. Fujimoto et al. · Journal of Medicinal Chemistry · 2009 · 58 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Design, Synthesis, and Properties of a Potent Inhibitor of<i>Pseudomonas aeruginosa</i>Deacetylase LpxC

Grazia Piizzi, David T. Parker, Yunshan Peng et al. · Journal of Medicinal Chemistry · 2017 · 47 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17