Lawrence MacPherson

Discovery of CGS 27023A, a Non-Peptidic, Potent, and Orally Active Stromelysin Inhibitor That Blocks Cartilage Degradation in Rabbits

Lawrence MacPherson, Erol K. Bayburt, Michael Capparelli et al. · Journal of Medicinal Chemistry · 1997 · 325 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Development of small-molecule probes that selectively kill cells induced to express mutant RAS

Michel Weïwer, Joshua A. Bittker, Timothy A. Lewis et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 238 citations

Medicine, Molecular Biology, Oncology +13

Pyrrolamide DNA Gyrase Inhibitors: Fragment-Based Nuclear Magnetic Resonance Screening To Identify Antibacterial Agents

Ann E. Eakin, Oluyinka Green, Neil J. Hales et al. · Antimicrobial Agents and Chemotherapy · 2011 · 134 citations

Pharmacy, Medicinal Chemistry, Molecular Biology +17

Inhibitors of poly ADP-ribose polymerase (PARP) induce apoptosis of myeloid leukemic cells: potential for therapy of myeloid leukemia and myelodysplastic syndromes

Terry J. Gaymes, Sydney Shall, Lawrence MacPherson et al. · Haematologica · 2009 · 84 citations · Full text

Medicine, Oncology, Pharmacology +17

Natural Selection, Protein Engineering, and the Last Riboorganism: Rational Model Building in Biochemistry

Steven A. Benner, Rudolf K. Allemann, Andrew D. Ellington et al. · Cold Spring Harbor Symposia on Quantitative Biology · 1987 · 70 citations

Life Sciences, Biochemistry, Biology +15