Ryan J. Holland

Synthesis and Chemical and Biological Comparison of Nitroxyl- and Nitric Oxide-Releasing Diazeniumdiolate-Based Aspirin Derivatives

Debashree Basudhar, Gaurav Bharadwaj, Robert Y.S. Cheng et al. · Journal of Medicinal Chemistry · 2013 · 77 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

The Nitric Oxide Prodrug JS-K Is Effective against Non–Small-Cell Lung Cancer Cells In Vitro and In Vivo: Involvement of Reactive Oxygen Species

Anna Maciąg, Harinath Chakrapani, Joseph E. Saavedra et al. · Journal of Pharmacology and Experimental Therapeutics · 2010 · 68 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Nitric oxide-releasing prodrug triggers cancer cell death through deregulation of cellular redox balance

Anna Maciąg, Ryan J. Holland, Y.-S. Robert Cheng et al. · Redox Biology · 2013 · 50 citations · Full text

Life Sciences, Cancer Biology, Medicinal Chemistry +17

The liver-selective NO donor, V-PYRRO/NO, protects against liver steatosis and improves postprandial glucose tolerance in mice fed high fat diet

Edyta Maślak, Piotr Zabielski, Kamila Kochan et al. · Biochemical Pharmacology · 2014 · 42 citations · Full text

Life Sciences, Endocrinology, Nutritional Sciences +14

Nitric Oxide (NO) Releasing Poly ADP-ribose Polymerase 1 (PARP-1) Inhibitors Targeted to Glutathione S-Transferase P1-Overexpressing Cancer Cells

Anna Maciąg, Ryan J. Holland, Youseung Kim et al. · Journal of Medicinal Chemistry · 2014 · 36 citations · Full text

Medicine, Oncology, Pharmacology +15