Joseph E. Saavedra

Complexes of ^.NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects

Chris M. Maragos, Deborah Morley, David A. Wink et al. · Journal of Medicinal Chemistry · 1991 · 721 citations

Natural Sciences, Chemistry, Pharmacology +13

Reactions of the bioregulatory agent nitric oxide in oxygenated aqueous media: Determination of the kinetics for oxidation and nitrosation by intermediates generated in the nitric oxide/oxygen reaction

David A. Wink, John F. Darbyshire, Raymond W. Nims et al. · Chemical Research in Toxicology · 1993 · 473 citations

Life Sciences, Chemistry, Toxicology +8

Key bioactive reaction products of the NO/H ₂ S interaction are S/N-hybrid species, polysulfides, and nitroxyl

Miriam M. Cortese‐Krott, Gunter Kuhnle, Alex Dyson et al. · Proceedings of the National Academy of Sciences · 2015 · 280 citations · Full text

Life Sciences, Biochemistry, Chemical Biology +14

Targeting Nitric Oxide (NO) Delivery<i>in Vivo</i>. Design of a Liver-Selective NO Donor Prodrug That Blocks Tumor Necrosis Factor-α-Induced Apoptosis and Toxicity in the Liver

Joseph E. Saavedra, Timothy R. Billiar, Debra L. Williams et al. · Journal of Medicinal Chemistry · 1997 · 275 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Measuring Fifteen Endogenous Estrogens Simultaneously in Human Urine by High-Performance Liquid Chromatography-Mass Spectrometry

Xia Xu, Timothy D. Veenstra, Stephen D. Fox et al. · Analytical Chemistry · 2005 · 227 citations

Pharmacy, Biochemistry, Endocrinology +16