Michael P. Thomas

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2.5K

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Active since

2006

Affiliations

Millennium Engineering and Integration (United States)(Current)

Michael P. Thomas is an author at Millennium Engineering and Integration (United States) specializing in oncology, molecular oncology, and molecular biology.

Publications per year

2006–2014

Publications

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

Teresa A. Soucy, Peter G. Smith, Michael A. Milhollen et al. · Nature · 2009 · 2K citations

Medicine, Medicinal Chemistry, Oncology +8

MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF-κB–dependent lymphoma

Michael A. Milhollen, Tary Traore, Jennifer Adams-Duffy et al. · Blood · 2010 · 323 citations · Full text

Medicine, Molecular Biology, Oncology +11

Identification of Small Molecules that Sensitize Resistant Tumor Cells to Tumor Necrosis Factor-Family Death Receptors

Aaron D. Schimmer, Michael P. Thomas, Rose Hurren et al. · Cancer Research · 2006 · 65 citations

Life Sciences, Oncology, Pharmacology +17

Nedd8-Activating Enzyme Inhibitor MLN4924 Provides Synergy with Mitomycin C through Interactions with ATR, BRCA1/BRCA2, and Chromatin Dynamics Pathways

Khristofer Garcia, Jonathan L. Blank, David C. Bouck et al. · Molecular Cancer Therapeutics · 2014 · 50 citations · Full text

Life Sciences, Molecular Biology, Oncology +16

Absolute Quantification of E1, Ubiquitin-Like Proteins and Nedd8–MLN4924 Adduct by Mass Spectrometry

Xiaofeng Yang, James E. Brownell, Qing Xu et al. · Cell Biochemistry and Biophysics · 2013 · 17 citations

Life Sciences, Biochemistry, Molecular Biology +17

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