Simon P. Newman

Cofactor competition between the ligand-bound oestrogen receptor and an intron 1 enhancer leads to oestrogen repression of ERBB2 expression in breast cancer

Simon P. Newman, Nicholas P Bates, Douglas Vernimmen et al. · Oncogene · 2000 · 109 citations

Systems Biology, Breast Oncology, Cofactor Competition +7

2-Substituted Estradiol Bis-sulfamates, Multitargeted Antitumor Agents:  Synthesis, In Vitro SAR, Protein Crystallography, and In Vivo Activity

Mathew P. Leese, Bertrand Leblond, Andrew Smith et al. · Journal of Medicinal Chemistry · 2006 · 107 citations · Full text

Chemoprevention Strategy, Vitro Sar, Carbonic Anhydrase Ii +20

17β‐hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone‐dependent breast cancer

Joanna M. Day, Paul Foster, Helena J. Tutill et al. · International Journal of Cancer · 2008 · 106 citations

Type 2 Diabetes Is Associated with Reduced ATP-Binding Cassette Transporter A1 Gene Expression, Protein and Function

Dipesh Patel, Christiane Albrecht, Darrell V. Pavitt et al. · PLoS ONE · 2011 · 81 citations · Full text

A-Ring-Substituted Estrogen-3-<i>O</i>-sulfamates:  Potent Multitargeted Anticancer Agents

Mathew P. Leese, Hatem A Hejaz, Mary F. Mahon et al. · Journal of Medicinal Chemistry · 2005 · 74 citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Endocrine-related Cancer +13