Degradation of DIAP1 by the N-end rule pathway is essential for regulating apoptosis

Mark Ditzel, Rebecca Wilson, Tencho Tenev, +4

Nature Cell Biology

Signaling PathwayCell RegulationApoptosisAutophagyCell Death +7

The interaction network of the chaperonin CCT

Carien Dekker, Peter C. Stirling, Elizabeth A. McCormack, +7

The EMBO Journal

Natural SciencesChaperonin CctBiological NetworkComputational BiologyInteraction Network +3

Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis

Sandra Kümper, Faraz K. Mardakheh, Afshan McCarthy, +8

eLife

Rock2 ActCytoskeletonCell CycleCellular PhysiologyTumor Biology +14

Trans‐activation of the DNA‐damage signalling protein kinase Chk2 by T‐loop exchange

Antony W. Oliver, Angela Paul, K. Boxall, +5

The EMBO Journal

Global Analysis of mRNA, Translation, and Protein Localization: Local Translation Is a Key Regulator of Cell Protrusions

Faraz K. Mardakheh, Angela Paul, Sandra Kümper, +5

Developmental Cell

Mrna LocalizationGlobal Quantitative AnalysisRna Binding ProteinsLong Non-coding RnaGlobal Analysis +14

An Eastern Cooperative Oncology Group evaluation of combinations of methyl-CCNU, mitomycin C, Adriamycin, and 5-fluorouracil in advanced measurable gastric cancer (EST 2277).

H. O. Douglass, Philip T. Lavin, Anouk Goudsmit, +1

Journal of Clinical Oncology

Mitomycin CCancer ManagementGastroenterologyPathologyPharmacotherapy +14

Phase II study of biochemical modulation of fluorouracil by low-dose PALA in patients with colorectal cancer.

Peter J. O’Dwyer, Angela Paul, Judy Walczak, +3

Journal of Clinical Oncology

Tumor BiologyOncologyGastrointestinal OncologyMedicineColorectal Cancer +13

Physical and Functional Interaction between Two Pluripotent Proteins, the Y-box DNA/RNA-binding Factor, YB-1, and the Multivalent Zinc Finger Factor, CTCF

Igor Chernukhin, Shaharum Shamsuddin, Abigail F. Robinson, +5

Journal of Biological Chemistry

GeneticsPluripotent ProteinsFunctional InteractionMolecular BiologyGene Characterization +20

Tyrosine Residues in Phospholipase Cγ2 Essential for the Enzyme Function in B-cell Signaling

Rosie Rodriguez, Miho Matsuda, Olga Perišić, +7

Journal of Biological Chemistry

Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1

Tencho Tenev, Anna Zachariou, Rebecca Wilson, +2

The EMBO Journal

Reductive StressMolecular PharmacologySignal TransductionCell RegulationApoptosis +7