Chen Liao

Dihydropyrazole derivatives as telomerase inhibitors: Structure-based design, synthesis, SAR and anticancer evaluation in vitro and in vivo

Yang Wang, Fei Cheng, Xiao Long Yuan et al. · European Journal of Medicinal Chemistry · 2016 · 57 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +15

Design, Synthesis, and Pharmacological Characterization of<i>N</i>-(4-(2 (6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1<i>H</i>)yl)ethyl)phenyl)quinazolin-4-amine Derivatives: Novel Inhibitors Reversing P-Glycoprotein-Mediated Multidrug Resistance

Qianqian Qiu, Baomin Liu, Jian Cui et al. · Journal of Medicinal Chemistry · 2017 · 46 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Discovery of novel 2-substituted-4-(2-fluorophenoxy) pyridine derivatives possessing pyrazolone and triazole moieties as dual c-Met/VEGFR-2 receptor tyrosine kinase inhibitors

Weijie Gu, Yuxuan Dai, Wei Shi et al. · Bioorganic Chemistry · 2017 · 42 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Discovery of phenylsulfonyl acetic acid derivatives with improved efficacy and safety as potent free fatty acid receptor 1 agonists for the treatment of type 2 diabetes

Zheng Li, Chunxia Liu, Xue Xu et al. · European Journal of Medicinal Chemistry · 2017 · 31 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9

Design, synthesis, and biological evaluation of thieno[2,3-d]pyrimidine derivatives as novel dual c-Met and VEGFR-2 kinase inhibitors

Jieming Li, Weijie Gu, Xinzhou Bi et al. · Bioorganic & Medicinal Chemistry · 2017 · 30 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16