Yasheng Zhu

Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance

Jinfang Zhang, Xia Bu, Haizhen Wang et al. · Nature · 2017 · 1K citations · Full text

Tumor Biology, Cancer Immune Surveillance, Cancer Immunosurveillance +12

Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression

Sujun Chen, Guanghui Zhu, Yue Yang et al. · Nature Cell Biology · 2021 · 487 citations

Tumor Heterogeneity, Medicine, Single Cell Sequencing +8

Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT–mTORC1 activation

Pingzhao Zhang, Dejie Wang, Yu Zhao et al. · Nature Medicine · 2017 · 298 citations · Full text

Bet Protein Stabilization, Medicine, Cancer Cell Biology +9

Development and prospective multicenter evaluation of the long noncoding RNA MALAT-1 as a diagnostic urinary biomarker for prostate cancer

Fubo Wang, Shancheng Ren, Rui Chen et al. · Oncotarget · 2014 · 180 citations · Full text

Truncated ERG Oncoproteins from TMPRSS2-ERG Fusions Are Resistant to SPOP-Mediated Proteasome Degradation

Jian An, Shancheng Ren, Stephen J. Murphy et al. · Molecular Cell · 2015 · 151 citations · Full text

Protein Function, Protein Expression, Natural Sciences +10