Widespread and Functional RNA Circularization in Localized Prostate Cancer

Sujun Chen, Vincent Huang, Xin Xu, +46

Cell

Functional Rna CircularizationProstatic DiseaseSystems BiologyMedicineTumor Biology +1

LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade

Wanqiang Sheng, Martin W. LaFleur, Thao H. Nguyen, +13

Cell

Tumor ImmunityImmune Checkpoint InhibitorTumor SuppressorEnables Checkpoint BlockadeMedicine +1

Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression

Sujun Chen, Guanghui Zhu, Yue Yang, +30

Nature Cell Biology

Tumor HeterogeneityMedicineSingle Cell SequencingCancer GenomicsSingle-cell Genomics +6

Risk SNP-Mediated Promoter-Enhancer Switching Drives Prostate Cancer through lncRNA PCAT19

Junjie T. Hua, Musaddeque Ahmed, Haiyang Guo, +20

Cell

GeneticsGene RegulationCancer GenomicsLong Non-coding RnaProstatic Disease +4

ONECUT2 is a driver of neuroendocrine prostate cancer

Haiyang Guo, Xinpei Ci, Musaddeque Ahmed, +37

Nature Communications

An Artificial Molecular Shuttle Operates in Lipid Bilayers for Ion Transport

Sujun Chen, Yichuan Wang, Ting Nie, +9

Journal of the American Chemical Society

Long-range enhancer activity determines <i>Myc</i> sensitivity to Notch inhibitors in T cell leukemia

Yumi Yashiro–Ohtani, Hongfang Wang, Chongzhi Zang, +17

Proceedings of the National Academy of Sciences

Transcriptional landscape of the human cell cycle

Yin Liu, Sujun Chen, Su Wang, +10

Proceedings of the National Academy of Sciences

ChiLin: a comprehensive ChIP-seq and DNase-seq quality control and analysis pipeline

Qian Qin, Shenglin Mei, Qiu Wu, +14

BMC Bioinformatics

Chromatin binding of FOXA1 is promoted by LSD1-mediated demethylation in prostate cancer

Shuai Gao, Sujun Chen, Dong Han, +19

Nature Genetics

Chromatin BindingChromatinTranscriptional RegulationChromatin RemodelingMedicine +7