Zhengping Wang

RAS nucleotide cycling underlies the SHP2 phosphatase dependence of mutant BRAF-, NF1- and RAS-driven cancers

Robert J. Nichols, Franziska Haderk, Carlos Stahlhut et al. · Nature Cell Biology · 2018 · 418 citations

Medicine, Molecular Biology, Oncology +16

Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy

Matthew Holderfield, Bianca J. Lee, Jingjing Jiang et al. · Nature · 2024 · 318 citations · Full text

Medicine, Oncology, Pharmacology +16

Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer

Urszula N. Wasko, Jingjing Jiang, Tanner C. Dalton et al. · Nature · 2024 · 175 citations · Full text

Medicine, Oncology, Pharmacology +17

Clinical Pharmacokinetics, Metabolism, and Drug-Drug Interaction of Carfilzomib

Zhengping Wang, Jinfu Yang, Christopher J. Kirk et al. · Drug Metabolism and Disposition · 2012 · 141 citations · Full text

Medicine, Clinical Pharmacokinetics, Pharmacology +15

Pharmacokinetics, Pharmacodynamics, Metabolism, Distribution, and Excretion of Carfilzomib in Rats

Jinfu Yang, Zhengping Wang, Ying Fang et al. · Drug Metabolism and Disposition · 2011 · 123 citations

Medicine, Pharmacokinetics, Pharmacology +10