Duane A. Burnett

The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)

Margarita García‐Calvo, JeanMarie Lisnock, Herbert G. Bull et al. · Proceedings of the National Academy of Sciences · 2005 · 768 citations

Life Sciences, Molecular Biology, Pharmacology +14

Discovery of 1-(4-Fluorophenyl)-(3<i>R</i>)-[3-(4-fluorophenyl)-(3<i>S</i>)- hydroxypropyl]-(4<i>S</i>)-(4-hydroxyphenyl)-2-azetidinone (SCH 58235):  A Designed, Potent, Orally Active Inhibitor of Cholesterol Absorption

Stuart B. Rosenblum, Tram Huynh, Adriano Afonso et al. · Journal of Medicinal Chemistry · 1998 · 355 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11

2-Azetidinones as Inhibitors of Cholesterol Absorption

Duane A. Burnett, Mary Ann Caplen, Harry R. Davis et al. · Journal of Medicinal Chemistry · 1994 · 239 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +5

The identification of intestinal scavenger receptor class B, type I (SR-BI) by expression cloning and its role in cholesterol absorption

S. Altmann, Harry R. Davis, Xiaorui Yao et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2002 · 160 citations

Life Sciences, Biochemistry, Molecular Biology +13

Pyrrolizidinone and indolizidinone synthesis: generation and intramolecular addition of .alpha.-acylamino radicals to olefins and allenes

Duane A. Burnett, Joong Kwon Choi, David J. Hart et al. · Journal of the American Chemical Society · 1984 · 147 citations

Natural Sciences, Chemistry, Medicinal Chemistry +5