Duane A. Burnett

The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)

Margarita García‐Calvo, JeanMarie Lisnock, Herbert G. Bull et al. · Proceedings of the National Academy of Sciences · 2005 · 759 citations · Full text

Biochemistry, Medicine, Niemann-pick C1-like 1 +9

Discovery of 1-(4-Fluorophenyl)-(3<i>R</i>)-[3-(4-fluorophenyl)-(3<i>S</i>)- hydroxypropyl]-(4<i>S</i>)-(4-hydroxyphenyl)-2-azetidinone (SCH 58235):  A Designed, Potent, Orally Active Inhibitor of Cholesterol Absorption

Stuart B. Rosenblum, Tram Huynh, Adriano Afonso et al. · Journal of Medicinal Chemistry · 1998 · 352 citations

Serum Total Cholesterol, Pharmaceutical Science, Pharmacotherapy +18

2-Azetidinones as Inhibitors of Cholesterol Absorption

Duane A. Burnett, Mary Ann Caplen, Harry R. Davis et al. · Journal of Medicinal Chemistry · 1994 · 238 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Chemistry +15

The identification of intestinal scavenger receptor class B, type I (SR-BI) by expression cloning and its role in cholesterol absorption

S. Altmann, Harry R. Davis, Xiaorui Yao et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2002 · 160 citations

Signal Transduction, Medicine, Liver Physiology +11

Pyrrolizidinone and indolizidinone synthesis: generation and intramolecular addition of .alpha.-acylamino radicals to olefins and allenes

Duane A. Burnett, Joong Kwon Choi, David J. Hart et al. · Journal of the American Chemical Society · 1984 · 146 citations

Combinatorial Chemistry, Molecular Sciences, Engineering +14