James M. Smith

The aging process of the nematode<i>Caenorhabditis elegans</i>in bacterial and axenic culture

Neil A. Croll, James M. Smith, Bert M. Zuckerman · Experimental Aging Research · 1977 · 115 citations

Life Sciences, Biology, Physiology +8

Structure-Based Design and Pharmacokinetic Optimization of Covalent Allosteric Inhibitors of the Mutant GTPase KRAS^G12C

Jason G. Kettle, Sharan K. Bagal, Sue Bickerton et al. · Journal of Medicinal Chemistry · 2020 · 85 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

SYNTHESIS AND ISOLATION OF A CRYSTALLINE SUBSTANCE WITH THE PROPERTIES OF A NEW B VITAMIN

John A. Brockman, Barbara Roth, Harry P. Broquist et al. · Journal of the American Chemical Society · 1950 · 62 citations

Natural Sciences, Biochemistry, Chemistry +14

Discovery of <i>N</i>-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1<i>H</i>-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors

Jason G. Kettle, Rana Anjum, Evan Barry et al. · Journal of Medicinal Chemistry · 2018 · 62 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Integrated behaviour in the feeding phase of Caenorhabditis elegans (Nematoda)

Neil A. Croll, James M. Smith · Journal of Zoology · 1978 · 46 citations

Life Sciences, Biology, Physiology +14