Rajesh Kumar

Multifunctional biocatalyst for conjugate reduction and reductive amination

Thomas W. Thorpe, James R. Marshall, Vanessa Harawa et al. · Nature · 2022 · 138 citations · Full text

Engineering, Biotechnology, Chemical Engineering +15

Biocatalytic reductive amination from discovery to commercial manufacturing applied to abrocitinib JAK1 inhibitor

Rajesh Kumar, Michael J. Karmilowicz, Dylan Burke et al. · Nature Catalysis · 2021 · 136 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Identification of Novel Bacterial Members of the Imine Reductase Enzyme Family that Perform Reductive Amination

Scott P. France, Roger M. Howard, Jeremy Steflik et al. · ChemCatChem · 2017 · 107 citations · Full text

Life Sciences, Biochemistry, Microbiology +17

Biocatalytic Routes to Enantiomerically Enriched Dibenz[<i>c</i>,<i>e</i>]azepines

Scott P. France, Godwin A. Aleku, Mahima Sharma et al. · Angewandte Chemie International Edition · 2017 · 93 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +16

A Computational Approach to Enzyme Design: Predicting ω-Aminotransferase Catalytic Activity Using Docking and MM-GBSA Scoring

Sarah Sirin, Rajesh Kumar, Michael J. Karmilowicz et al. · Journal of Chemical Information and Modeling · 2014 · 91 citations

Life Sciences, Biochemistry, Molecular Biology +17