Roger M. Howard

One-Pot Cascade Synthesis of Mono- and Disubstituted Piperidines and Pyrrolidines using Carboxylic Acid Reductase (CAR), ω-Transaminase (ω-TA), and Imine Reductase (IRED) Biocatalysts

Scott P. France, Shahed Hussain, Andrew M. Hill et al. · ACS Catalysis · 2016 · 199 citations

Engineering, Chiral Imine, Organic Chemistry +17

Multifunctional biocatalyst for conjugate reduction and reductive amination

Thomas W. Thorpe, James R. Marshall, Vanessa Harawa et al. · Nature · 2022 · 128 citations · Full text

Biocatalysis, Chemical Engineering, Bioconjugation +1

Identification of Novel Bacterial Members of the Imine Reductase Enzyme Family that Perform Reductive Amination

Scott P. France, Roger M. Howard, Jeremy Steflik et al. · ChemCatChem · 2017 · 104 citations · Full text

Biochemistry, Natural Sciences, Biocatalysis +13

Biocatalytic Routes to Enantiomerically Enriched Dibenz[<i>c</i>,<i>e</i>]azepines

Scott P. France, Godwin A. Aleku, Mahima Sharma et al. · Angewandte Chemie International Edition · 2017 · 91 citations · Full text

A PP2A regulatory subunit positively regulates Ras-mediated signaling during Caenorhabditis elegans vulval induction

Derek Sieburth, Meera V. Sundaram, Roger M. Howard et al. · Genes & Development · 1999 · 89 citations · Full text