Jeremy Steflik

Excitatory monocyte chemoattractant protein-1 signaling is up-regulated in sensory neurons after chronic compression of the dorsal root ganglion

Fletcher A. White, Jihu Sun, Stephen M. Waters et al. · Proceedings of the National Academy of Sciences · 2005 · 368 citations · Full text

Biocatalytic reductive amination from discovery to commercial manufacturing applied to abrocitinib JAK1 inhibitor

Rajesh Kumar, Michael J. Karmilowicz, Dylan Burke et al. · Nature Catalysis · 2021 · 129 citations

Medicinal Chemistry, Engineering, Commercial Manufacturing +10

Identification of Novel Bacterial Members of the Imine Reductase Enzyme Family that Perform Reductive Amination

Scott P. France, Roger M. Howard, Jeremy Steflik et al. · ChemCatChem · 2017 · 104 citations · Full text

Biochemistry, Natural Sciences, Biocatalysis +13

Biocatalytic Routes to Enantiomerically Enriched Dibenz[<i>c</i>,<i>e</i>]azepines

Scott P. France, Godwin A. Aleku, Mahima Sharma et al. · Angewandte Chemie International Edition · 2017 · 91 citations · Full text

Chemoenzymatic Asymmetric Synthesis of Pregabalin Precursors via Asymmetric Bioreduction of β-Cyanoacrylate Esters Using Ene-Reductases

Christoph K. Winkler, Dorina Clay, Simon B. Davies et al. · The Journal of Organic Chemistry · 2013 · 89 citations · Full text

Engineering, Organic Chemistry, Pregabalin Precursors +16