Michael J. Karmilowicz

Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.

Stephan Grissmer, A. N. Nguyen, Jayashree Aiyar et al. · Molecular Pharmacology · 1994 · 780 citations

Natural Sciences, Biophysics, Pharmacology +17

Autocrine Induction of Collagenase by Serum Amyloid A-Like and β ₂ -Microglobulin-Like Proteins

Constance Brinckerhoff, Teresa I. Mitchell, Michael J. Karmilowicz et al. · Science · 1989 · 162 citations

Life Sciences, Biochemistry, Molecular Biology +15

Biocatalytic reductive amination from discovery to commercial manufacturing applied to abrocitinib JAK1 inhibitor

Rajesh Kumar, Michael J. Karmilowicz, Dylan Burke et al. · Nature Catalysis · 2021 · 136 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Redesigning and characterizing the substrate specificity and activity of Vibrio fluvialis aminotransferase for the synthesis of imagabalin

Katarina S. Midelfort, R. Pravin Kumar, Seungil Han et al. · Protein Engineering Design and Selection · 2012 · 135 citations · Full text

Life Sciences, Biochemistry, Biotechnology +17

Concentration-Dependent Modulation of Amyloid-β in Vivo and in Vitro Using the γ-Secretase Inhibitor, LY-450139

Thomas A. Lanz, Michael J. Karmilowicz, Kathleen M. Wood et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 133 citations

Medicine, Neuroscience, Pharmacology +13