Cheng Chang

Human Pregnane X Receptor Antagonists and Agonists Define Molecular Requirements for Different Binding Sites

Sean Ekins, Cheng Chang, Sridhar Mani et al. · Molecular Pharmacology · 2007 · 146 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Plasma Protein Binding of Challenging Compounds

Keith Riccardi, Shannon Cawley, Phillip D. Yates et al. · Journal of Pharmaceutical Sciences · 2015 · 117 citations

Pharmacy, Biochemistry, Pharmacology +12

Anti-Malarial Drug Artesunate Attenuates Experimental Allergic Asthma via Inhibition of the Phosphoinositide 3-Kinase/Akt Pathway

Cheng Chang, Wanxing Eugene Ho, Fera Y. Goh et al. · PLoS ONE · 2011 · 115 citations · Full text

Medicine, Immunology, Pharmacology +17

Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors

Andrea M. Zuhl, Charles E. Nolan, Michael A. Brodney et al. · Nature Communications · 2016 · 77 citations · Full text

Medicine, Pharmacology, Toxicology +15

Computational Models to Assign Biopharmaceutics Drug Disposition Classification from Molecular Structure

Akash Khandelwal, Praveen M. Bahadduri, Cheng Chang et al. · Pharmaceutical Research · 2007 · 63 citations

Pharmacy, Pharmacokinetics, Pharmacology +16