Cheng Chang

Human Pregnane X Receptor Antagonists and Agonists Define Molecular Requirements for Different Binding Sites

Sean Ekins, Cheng Chang, Sridhar Mani et al. · Molecular Pharmacology · 2007 · 146 citations

Anti-Malarial Drug Artesunate Attenuates Experimental Allergic Asthma via Inhibition of the Phosphoinositide 3-Kinase/Akt Pathway

Cheng Chang, Wanxing Eugene Ho, Fera Y. Goh et al. · PLoS ONE · 2011 · 115 citations · Full text

Plasma Protein Binding of Challenging Compounds

Keith Riccardi, Shannon Cawley, Phillip D. Yates et al. · Journal of Pharmaceutical Sciences · 2015 · 110 citations

Protein Chemistry, Protein Assembly, Biochemistry +4

Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors

Andrea M. Zuhl, Charles E. Nolan, Michael A. Brodney et al. · Nature Communications · 2016 · 76 citations · Full text

Computational Models to Assign Biopharmaceutics Drug Disposition Classification from Molecular Structure

Akash Khandelwal, Praveen M. Bahadduri, Cheng Chang et al. · Pharmaceutical Research · 2007 · 63 citations

Medicinal Chemistry, Drug Target, Biochemistry +7