Javier de Vicente

Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson’s disease

Danna Jennings, Sarah Huntwork‐Rodriguez, Anastasia G. Henry et al. · Science Translational Medicine · 2022 · 230 citations

Discovery of a Novel Series of Potent Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B

Ryan C. Schoenfeld, David L. Bourdet, Ken A. Brameld et al. · Journal of Medicinal Chemistry · 2013 · 36 citations · Full text

Hepatitis C Virus, Molecular Biology, Antiviral Drug +16

Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative Bacteria

Colin K. Skepper, Duncan Armstrong, Carl J. Balibar et al. · Journal of Medicinal Chemistry · 2020 · 36 citations · Full text

Non-nucleoside inhibitors of HCV polymerase NS5B. Part 2: Synthesis and structure–activity relationships of benzothiazine-substituted quinolinediones

Javier de Vicente, R. Hendricks, David B. Smith et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 35 citations

Antiviral Compound, Viral Polymerase Structure, Biochemistry +8

Non-nucleoside inhibitors of HCV polymerase NS5B. Part 4: Structure-based design, synthesis, and biological evaluation of benzo[d]isothiazole-1,1-dioxides

Javier de Vicente, R. Hendricks, David B. Smith et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 35 citations · Full text

Combinatorial Chemistry, Antiviral Compound, Biochemistry +8