Thomas E. Hughes

Determinants of the Impaired Secretion of Glucagon-Like Peptide-1 in Type 2 Diabetic Patients

M. Toft-Nielsen, Mette Brimnes Damholt, Sten Madsbad et al. · The Journal of Clinical Endocrinology & Metabolism · 2001 · 835 citations

1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(<i>S</i>)-pyrrolidine:  A Potent, Selective, and Orally Bioavailable Dipeptidyl Peptidase IV Inhibitor with Antihyperglycemic Properties

Edwin B. Villhauer, J. A. Brinkman, Goli B. Naderi et al. · Journal of Medicinal Chemistry · 2003 · 609 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Science +14

Sec3p Is a Spatial Landmark for Polarized Secretion in Budding Yeast

Fern P. Finger, Thomas E. Hughes, Peter Novick · Cell · 1998 · 376 citations · Full text

Ibrutinib for previously untreated and relapsed or refractory chronic lymphocytic leukaemia with TP53 aberrations: a phase 2, single-arm trial

Mohammed Farooqui, Janet Valdez, Sabrina Martyr et al. · The Lancet Oncology · 2014 · 365 citations · Full text

Hematological Malignancy, Lymphoid Neoplasia, Tp53 Aberrations +8

Common Missense Variant in the Glucokinase Regulatory Protein Gene Is Associated With Increased Plasma Triglyceride and C-Reactive Protein but Lower Fasting Glucose Concentrations

Marju Orho‐Melander, Olle Melander, Candace Guiducci et al. · Diabetes · 2008 · 317 citations · Full text