Ying Lin

Cleavage of the death domain kinase RIP by Caspase-8 prompts TNF-induced apoptosis

Ying Lin, Anne Devin, Yolanda Rodríguez et al. · Genes & Development · 1999 · 820 citations · Full text

Apoptosis, Immunology, Cell Death +17

Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation

Wei Qi, Homan Chan, Lin Teng et al. · Proceedings of the National Academy of Sciences · 2012 · 542 citations · Full text

Selective Inhibition, Tumor Biology, Methyl Group +15

Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5

Konstantinos J. Mavrakis, E. Robert McDonald, Michael R. Schlabach et al. · Science · 2016 · 538 citations

An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED

Wei Qi, Kehao Zhao, Justin Gu et al. · Nature Chemical Biology · 2017 · 313 citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +7

Mesenchymal stem cell exosomes promote immunosuppression of regulatory T cells in asthma

Yumo Du, Yongxun Zhuansun, Rui Chen et al. · Experimental Cell Research · 2017 · 220 citations

Asthma, Extracellular Vesicles, Cell Therapy +12