Hao He

Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis

Leslie O. Goodwin, Erik Splinter, Tiffany L. Davis et al. · Genome Research · 2019 · 215 citations · Full text

Engineering, Large-scale Discovery, Transgenic Mouse Models +20

Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5

Guillermo Senisterra, Hong Wu, Abdellah Allali‐Hassani et al. · Biochemical Journal · 2012 · 158 citations · Full text

Chromatin interaction analyses elucidate the roles of PRC2-bound silencers in mouse development

Chew Yee Ngan, Chee‐Hong Wong, Harianto Tjong et al. · Nature Genetics · 2020 · 157 citations · Full text

Chromatin, Developmental Biology, Chromatin Structure +13

Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations

Hong Wu, Hong Zeng, Aiping Dong et al. · PLoS ONE · 2013 · 133 citations · Full text

Histone Modifications, Catalytic Domain, Engineering +20

PmiREN2.0: from data annotation to functional exploration of plant microRNAs

Zhonglong Guo, Zheng Kuang, Yongxin Zhao et al. · Nucleic Acids Research · 2021 · 106 citations · Full text