Aiping Dong

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

Masoud Vedadi, Dalia Baršytė-Lovejoy, Feng Liu et al. · Nature Chemical Biology · 2011 · 527 citations

Signal Transduction, Cellular Enzymology, Biochemistry +12

Structure and Biochemical Functions of SIRT6

Patricia W. Pan, Jessica L. Feldman, Mark Devries et al. · Journal of Biological Chemistry · 2011 · 305 citations · Full text

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia

Florian Grebien, Masoud Vedadi, Matthäus Getlik et al. · Nature Chemical Biology · 2015 · 282 citations · Full text

Hematological Malignancy, Medicine, Pharmacology +4

A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases

Mohammad S. Eram, Yudao Shen, Magdalena M. Szewczyk et al. · ACS Chemical Biology · 2015 · 280 citations · Full text

Drug Target, Epigenetic Change, Molecular Biology +23

Structural Basis of Inhibition of the Human NAD+-Dependent Deacetylase SIRT5 by Suramin

A. Schuetz, Jinrong Min, T. Antoshenko et al. · Structure · 2007 · 257 citations · Full text

Molecular Pharmacology, Aldo-keto Reductase, Cellular Enzymology +6